Searchable abstracts of presentations at key conferences in endocrinology

ea0037ep357 | Diabetes (pathiophysiology & epitemiology) | ECE2015

The role of TCF7L2 polymorphism in the development of type 2 diabetes in subjects with metabolic syndrome

Katsoulis Konstantinos , Paschou Stavroula , Hatzi Elissavet , Tigas Stelios , Georgiou Ioannis , Tsatsoulis Agathocles

Introduction: Transcription factor 7 like-2 (TCF7L2) gene variants (rs12255372 and rs7903146) have been consistently shown to raise genetic risk for type 2 diabetes (T2D). The aim of this study was to investigate the possible role of these variants in the development of dysglycemia (T2D or impaired fasting glucose (IFG)) in patients with metabolic syndrome (MS).Patients and methods: The study population consisted of 228 patients with MS who were...